WEBINAR Keeping it Real: Why P450 Assays are Required to Predict Human Drug Responses Using Liver-on-a-Chip 12 October 2022

FREE PROMEGA WEBINAR

Date : 12th October 2022
Time : 11 am (Indonesia)

In this webinar we will discuss Despite billions in investment, most drugs never reach the market because preclinical experiments fail to predict effects. Standard in vitro assays lack physiological relevance, whilst animal models lack human relevance. By better replicating human organs and tissues in the laboratory, PhysioMimix™ Organ-on-a-chip systems address these limitations. Human Liver-on-a-chip models are used to predict drug metabolism and toxicity, or to model disease for efficacy assessments. Monitoring the health and functionality of primary human cells throughout long-term culture is essential. In this webinar, Dr. Darren Heywood from Promega will introduce cell-based assays optimized for 3D culture, including a suite of P450-Glo™ Assays. Dr. Atefeh Mobasseri from CN Bio, will then discuss the use of Promega P450-Glo™ assay kit as a critical step in cell quality control to assess the metabolic activity of a liver-on-a-chip model.

, :

• Why there’s a pressing need for preclinical assays that predict human responses to drugs
• How organ-on-a-chip addresses traditional in vitro and animal model limitation to provide a solution
• The importance of quality controls during development of complex 3D models
• How Promega’s luminescent P450-Glo™M CYP450 activity assay work and how they can be applied to 3D models

Link Webinar : https://bit.ly/3ek5N3B