Description
Descriptions :
All areas of the BRCA ½ gene which is the representative cause of hereditary breast cancer are analyzed to diagnose a person’s risk of breast cancer. Mutations in the BRCA ½ gene greatly increase the risk of breast cancer. It is available for both germline and somatic variants detecting SNP and InDel for 53 genes and CNV for BRCA1/2 genes.
Who to test for BRCA
- Early onset breast cancer (under 50 years of age)
- Bilateral or multiple breast cancer
- Diagnosed with both breast and ovarian cancer
- Family history of breast and/or ovarian cancer
- Two or more BRCA 1 or 2 related cancers on a single family member
| Sample types | Concentrations | |
| AxenTM BRCA 1/2 |
Blood or Gdna |
5ml of blood 200ng/ul |
| AxenTM BRCA Premium with 53 HBOC related genes |
Somatic variants Germline variants |
500ng from FFPE 300ng of dna |
| MLPA for BRCA1/2 genes | gDNA | 100ng of dna |
