Description
Glucose is a key metabolite for most cells. In the resting state, glucose is metabolized to pyruvate by glycolysis, and then through the tricarboxylic acid (TCA) cycle. Ultimately each carbon is metabolized to CO2. Along the path, ATP is generated through substrate level phosphorylation in glycolysis and more efficiently in the TCA cycle through oxidative phosphorylation.
Once signals are received for growth, the cell increases glucose uptake and metabolizes it through glycolysis. Some glycolytic intermediates are diverted to biosynthetic pathways to create raw materials for synthesis of a new cell. Glucose-based ATP production is mostly through substrate phosphorylation with lactate secretion rather than entrance into the TCA cycle. Growing cells increase uptake of glutamine to feed intermediates into the TCA cycle to maintain ATP production.
| Product | Packaging size | Brand | Catalog |
| Glycogen-Glo™ Assay | 5 ml | Promega | CS1823B01 |
| 50ml | Promega | CS1823B02 | |
| Glucose-Glo™ Assay | 5 ml | Promega | J6021 |
| 50ml | Promega | J6022 | |
| Lactate-Glo™ Assay | 5 ml | Promega | J5021 |
| 50ml | Promega | J5022 |
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