In preparation for eventual “test-all” legislation for procession sexual assault kits, the Forensic Biology Unit at the Palm Beach County Sheriff’s Office (FBU) began the quest for a solution to increase casework handling capacity, without increasing staff. With a validating Y-screening, direct-to-DNA workflow, the FBU could triage samples to improve processing efficiency. This webinar details […]
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Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that recruit target proteins for degradation via the ubiquitin proteasomal pathway. Traditional small-molecule drugs have focused on inhibition of the target protein; however, many targets do not have accessible binding sites. PROTACs offer an exciting opportunity to “drug the undruggable” by tagging the target for degradation. This webinar introduces […]
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