19/05/2021 What are the different types of 3D models? How can I evaluate cell-based assays for use in 3D cultures? What assays are optimized for 3D? Our experts will answer your questions on 3D cultures and assays in this Q&A webinar. You will learn about: What are the different types of 3D models? How can […]
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12/05/2021 Many journals and grant bodies now stipulate Cell Line Authentication (CLA) as a pre-requisite for submission. In this webinar, we will discuss the importance of confirming the identity and sterility of cell lines, explaining when these checks should be carried out, to what standards and why it is so important to the world of […]
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06/05/2021 The Dynamics of Compound Profiling: Using Signaling Kinetic Assays to Shape Early-Stage Drug DiscoveryIn vitro early-stage compound profiling often focuses on single timepoint measurements of drug action. However, in vivo, drug action occurs not at equilibrium, but within a highly dynamic system. This webinar will explore how measuring the kinetics of drug-target interaction and […]
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Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that recruit target proteins for degradation via the ubiquitin proteasomal pathway. Traditional small-molecule drugs have focused on inhibition of the target protein; however, many targets do not have accessible binding sites. PROTACs offer an exciting opportunity to “drug the undruggable” by tagging the target for degradation. This webinar introduces […]
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